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Maribel Díaz-Ricart, Ph.D.

 
Maribel Díaz-Ricart Endothelial cells (HUVEC) in culture (left image). Exposure of HUVEC to serum from patients with a chronic inflammatory disease (right image) causes endothelial damage, with retraction and release of cells, exposure of the surface to circulating cells, with the adhesion of platelets to the extracellular matrix and attachment of leukocytes (insert) to the remaining cells
 

Pharmacist, Research Coordinator. Laboratory of Platelet and Vascular Biology Research.


Research Interest

  • Platelet biochemistry and physiology.
  • Platelet activation and signaling mechanisms associated with cytoskeletal proteins.
  • Signal transduction mechanisms in platelets activated by adhesion to adhesive substrata under flow conditions.
  • Adhesion studies and signaling mechanisms in CD34+ hematopoietic progenitors.
  • Signaling pathways in endothelial cells.
  • Mechanisms of endothelial dysfunction. Study of potential preventive strategies.


Techniques

  • Isolation of cells from tissues and cell cultures.
  • Techniques to explore platelet function.
  • Annular, parallel and microchamber perfusion systems. Morphometric techniques.
  • Light and confocal microscopy.
  • Protein isolation and protein techniques.
  • Proteomic analysis.
  • Writing and editing of scientific texts.


Publications

  • Click here to link the full list of publications of Maribel Díaz-Ricart in MedLine.


 
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Platelet Research Laboratory
Hospital Clínic - IDIBAPS
Barcelona, Catalonia
Spain