Welcome to the Platelet Research Laboratory
website. This site provides a brief description of the
Platelet Research Laboratory aims and services as well
as some basic concepts about platelet function and the
importance of its study.
The Platelet Research Laboratory focuses its efforts on the study of basic mechanisms involved in alterations of hemostasis the involvement of the vessel wall and their implications in the the pathogenesis of thrombosis.
A main objective of the Platelet Research Laboratory is the careful analysis of congenital and acquired deficiencies of hemostasis, and its correction through pharmacological and transfusional strategies. This site will also considere the critical role of modifications in the reactivity of the vessel wall in dysfunctional hemostasis.
The need of transforming the promise of the genomics
and proteomics revolution into a pipeline of safe and
effective new drugs is a key challenge of pharmaceutical
companies. Another important objective of our laboratories
is to help breaking the bottleneck in drug discovery.
To achieve these objectives we actively contribute
to the development of the following research lines:
- In-depth knowledge of the mechanisms involved in
the interaction of platelets with vascular surfaces
and with other physiologic cell types (endothelial
cells, leukocytes and erythrocytes) or pathological
- Evaluation and screening of antithrombotic and prohemostatic strategies.
- Obtention of safer and hemostatically effective
blood derivatives for transfusional purposes.
The Platelet Research Laboratory employs state-of-the-art
technologies and well-defined experimental models that
take into consideration vascular flow conditions.